Introduction

TRILOS ND500 is the pilot-scale production model homogenizer. It is suitable for pilot-scale production and process validation. Its flow rate reaches maximum 60L/h when the pressure keeps at 3000bar. The position of inlet and outlet are at the right side of the homogenizer for cyclic homogenization. The upper inlet is customizable if required. TRILOS ND500 is available for TRILOS Automated Homogenization System.

Features
  •  Performance:Ultra-high pressure&Sub-Micron Homogenization

  •  Microfluidics: X/Y/Z-type Diamond Interaction Chamber

  •  Smart: Touchscreen & IoT Platform

  •  Versatile: A Wide Range of Application

  •  Cooling: Circulating Water Bath

  •  Cleaning: CIP/SIP

  •  Resistance: Acid & Alkali/High Temperature

  •  Portable: Movable Design

  •  Scalable:Horizontal Scalability

 

Performance:Ultra-high pressure&Sub-Micron Homogenization

The maximum working pressure of the TRILOS UHP Nano Homogenizer Series achieves 4000bar. They are capable of reducing the particle size down to sub-micron level and nano level, ensuring uniform particle distribution and particle stability.

Microfluidics: X/Y/Z-type Diamond Interaction Chamber

The interaction chamber is made of 316L stainless steel outside and made of synthetic diamond inside, which has high pressure resistance and wear resistance. As the material passes through the interaction chamber, it is exposed to intense shear, turbulence, cavitation, and impact forces generated by ultra-high pressure and the fixed geometry. The fixed geometry is X/Y/Z-type. Each type has a different characteristics and a wide range of application. The following table demonstrates the differences among them. These combined effects effectively reduce particle size, break down agglomerates, and create highly uniform dispersion or emulsification.

TRILOS uses special design on the microchannels within the interaction chamber to adapt particle size and ultra-high pressure. Therefore, it does not block when large particles pass under high pressure.

Geometry

Energy Intensity

Shear Force

Cavitation

Application

X-type

 High

Moderate

Moderate

Nanomaterials / Food & Beverage

Y-type

Very High

High

Strong

Nanoemulsion / Nanosuspension / Cell Disruption

Z-type

Extremely High

Very High

Very Strong

Nanomaterials / Liposomes / Graphene

Comparison of X/Y/Z-type Fixed Geometry Interaction Chamber

 

 

Smart: Touchscreen & IoT Platform

TRILOS UHP Nano Homogenizer series use a 10 inch digital touchscreen, displaying a pressure-time graph and real-time parameter on the homepage. Pressure is controlled by a rotary. Historical data can be saved and viewed.

TRILOS IoT platform pioneers in the high pressure homogenizer industry. The IoT platform is a key medium to automation, where enables the connection between homogenizer and tablet via the internet and bluetooth. TRILOS IoT platform allows users to remotely control and view the historical data.

Versatile: A Wide Range of Application

TRILOS UHP Nano Homogenizers are essential in industries where nano-scale control, high stability, and consistent product quality are critical. The equipment achieves nano-dispersion, nano-emulsion, deagglomeration, cell disruption, efficiently improving uniformity and stability of the material and narrowing particle size distribution.

Cooling: Circulating Water Bath

TRILOS circulating water bath can transport the low-temperature cooled water into the UHP Nano Homogenizers to take away the heat generated by the operation of intensifier pump. The high-temperature hot water is then transported to the water bath for cooling. This cyclic cooling exchange achieves temperature control of the pump.

Cleaning: CIP/SIP

TRILOS UHP Nano Homogenizers support CIP (Clean-in-Place) and SIP (Sterilize-in-Place). The port for CIP or SIP is external. The dead corners can even be cleaned and sterilized.

Resistance: Acid & Alkali/High Temperature

TRILOS UHP Nano Homogenizers are resistant to acid and alkali solution (less than 3%). They are temporarily resistant to strong acid and alkali and high temperature (lower than 600℃).

Portable: Movable Design

TRILOS uses a vertical and portable design on the UHP Nano Homogenizer series. They are installed with leveling casters for transport convenience.

Scalable:Horizontal Scalability

The ND500 and ND1000 are available for horizontal scalability. We can add more machines to the production line to fulfill yield and quality requirement.

Specifications

Parameter

Metric

Imperial

Working Pressure

0–4000 bar (0–400 MPa)

0–58000 psi

Flow Rate

60 L/h

15.85 gal/h

Min. Input Volume

1000 mL (1 L)

33.8 fl oz (0.26 gal)

Max. Material Particle Size

< 300 μm

< 0.012 in

Max. Material Viscosity

< 10,000 cP

< 10,000 cP

Max. Temperature

≤ 90 °C

≤ 194 °F

Dimensions (L × W × H)

960 × 700 × 1260 mm

37.8 × 27.6 × 49.6 in

Applications

Advanced&Functional Materials: nano-slurry for ceramics / pigments&inks / battery materials&conductive pastes / graphene&CNT / metal slurry like Ni/Cu slurry

Cosmetics&Personal Care: serums / lotions / creams

Food & Beverage: fruit & vegetable juice / milk / functional beverages

Biotechnology&Life Sciences: cell disruption of bacteria&yeast& microalgae / protein&enzyme&nucleic acid extraction

Pharmaceuticals: nanosuspensions / liposome / nano-carrier systems

Chemicals & Fine Chemicals: emulsion and suspension systems / functional additives / specialty chemicals

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