Introduction
TRILOS ND500 is the pilot-scale production model homogenizer. It is suitable for pilot-scale production and process validation. Its flow rate reaches maximum 60L/h when the pressure keeps at 3000bar. The position of inlet and outlet are at the left side of the homogenizer for cyclic homogenization. The upper inlet is customizable if required. TRILOS ND500 is available for TRILOS Automated Homogenization System.
Features
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Performance: Ultra-High Pressure & Nano-Scale Homogenization
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Microfluidics: X/Y/Z-Type Diamond Interaction Chamber
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Smart: Touchscreen Control & IoT Platform
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Versatile: A Wide Range of Application
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Cooling: Circulating Water Bath
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Cleaning: CIP/SIP
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Resistance: Acid & Alkali / High Temperature
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Portable: Movable Design
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Scalable:Horizontal Scalability
Performance: Ultra-High Pressure & Nano-Scale Homogenization
The maximum working pressure of the UHP Nano Homogenizer Series achieves 4000bar. They are capable of reducing the particle size down to sub-micron level and nano level, ensuring uniform particle distribution and particle stability.
Microfluidics: X/Y/Z-Type Diamond Interaction Chamber
The interaction chamber is made of 316L stainless steel outside and made of synthetic diamond inside, which has high pressure resistance and wear resistance. As the material passes through the interaction chamber, it is exposed to intense shear, turbulence, cavitation, and impact forces generated by ultra-high pressure and the fixed geometry. The fixed geometry is X/Y/Z-type. Each type has a different characteristics and a wide range of application. The following table demonstrates the differences among them. These combined effects effectively reduce particle size, break down agglomerates, and create highly uniform dispersion or emulsification.
TRILOS uses special design on the microchannels within the interaction chamber to adapt particle size and ultra-high pressure. As a result, it does not block when large particles pass under high pressure.
|
Geometry |
Energy Intensity |
Shear Force |
Cavitation |
Application |
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X-type |
High |
Moderate |
Moderate |
Nanomaterials / Food & Beverage |
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Y-type |
Very High |
High |
Strong |
Nanoemulsion / Nanosuspension / Cell Disruption |
|
Z-type |
Extremely High |
Very High |
Very Strong |
Nanomaterials / Liposomes / Graphene |
Comparison of X/Y/Z-type Fixed Geometry Interaction Chamber
Smart:Touchscreen Control & IoT Platform
The UHP Nano Homogenizer series use a 10 inch digital touchscreen, displaying a pressure-time graph and real-time parameter on the homepage. Pressure is controlled by a rotary. Historical data is saved and can be viewed by the users.
TRILOS IoT platform pioneers in the high pressure homogenizer industry. The IoT platform is a key medium to automation, where enables the connection between homogenizer and tablet via the internet. TRILOS IoT platform allows users to remotely control and view the history data of the UHP Nano Homogenizer series.
Versatile: A Wide Range of Application
UHP Nano Homogenizer Series achieves nano-dispersion, nano-emulsion, deagglomeration, cell disruption, efficiently improving uniformity and stability of the material and narrowing particle size distribution.
Cooling: Circulating Water Bath
TRILOS circulating water bath can transport the low-temperature cooled water into the UHP Nano Homogenizer to take away the heat generated by the operation of intensifier pump. The high-temperature hot water is then transported to the water bath for cooling. This cyclic cooling exchange achieves temperature control of the pump.
Cleaning: CIP/SIP
UHP Nano Homogenizer supports CIP (Clean-in-Place) and SIP (Sterilize-in-Place). The port for CIP or SIP is external. The dead corners can even be cleaned and sterilized.
Resistance: Acid & Alkali / High Temperature
UHP Nano Homogenizer is resistant to acid and alkali solution (less than 3%). They are temporarily resistant to strong acid and alkali and high temperature (lower than 600℃).
Portable: Movable Design
TRILOS uses a vertical and portable design on the UHP Nano Homogenizers series due to their heavy weight. They are installed with leveling casters for transport convenience.
Scalable:Horizontal Scalability
The ND500 and ND1000 are available for horizontal scalability. We can add more machines to the production line to fulfill yield and quality requirement.
Specifications
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Parameter |
Metric |
Imperial |
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Working Pressure |
0–4000 bar (0–400 MPa) |
0–58000 psi |
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Flow Rate |
60 L/h |
15.85 gal/h |
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Min. Input Volume |
1000 mL (1 L) |
33.8 fl oz (0.26 gal) |
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Max. Material Particle Size |
< 300 μm |
< 0.012 in |
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Max. Material Viscosity |
< 10,000 cP |
< 10,000 cP |
|
Max. Temperature |
≤ 90 °C |
≤ 194 °F |
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Dimensions (L × W × H) |
960 × 700 × 1260 mm |
37.8 × 27.6 × 49.6 in |
Applications
Advanced & Functional Materials: nano-slurry for ceramics / pigments & inks / battery materials & conductive pastes / graphene & CNT / metal slurry (Ni/Cu slurry)
Cosmetics & Personal Care: serums / lotions / creams
Food & Beverage: fruit & vegetable juice / milk
Biotechnology & Life Sciences: cell disruption of bacteria / protein & nucleic acid extraction
Pharmaceuticals: nanosuspensions / liposome / nano-carrier systems
Chemicals & Fine Chemicals: emulsion / suspension / functional additives / specialty chemicals
